Rock Springs Run State Reserve is nearly 14,000 acres of a wide variety of plant communities typically found throughout Central Florida's landscape.

The property was purchased in March 1983 for habitat preservation, watershed protection and to provide recreational opportunities in the Central Florida area. Additional purchases in 1991 and 1995 have formed a vast wilderness in Orange and Lake Counties.

The Wekiva River Basin includes Wekiwa Springs Run, Rock Springs Run, the Wekiva River, Blackwater Creek and Seminole Creek. These waterways comprise the first Congressionally designated Wild and Scenic River in Florida.

Native American Indians valued the abundance of wildlife in this area. These Native Americans lived here before the arrival of the Spanish in 1513, but within 200 years they were eliminated from their native land. Many mounds, or kitchen middens, are known to exist along the Wekiva River and Rock Springs Run. The mounds are the only visible remains of their presence on the reserve and are protected for future archaeological investigations.

Florida statutes prohibit the destruction or removal of artifacts from these sites.